HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidinium chloride → (R)-3-Phenyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidinium chloride | HCID 82509 | — |
| Reactant | Disodium | HCID 141233 | — |
| Reactant | (R)-2-(4-fluoro-benzenesulfonylamino)-3-phenyl-propionic acid | HCID 737254 | — |
| Product | (R)-3-Phenyl-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid | HCID 54561606 | — |
Reaction Steps
In a manner similar to Example 3(b), (R)-2-(4-fluoro-benzenesulfonylamino)-3-phenyl-propionic acid, disodium salt was condensed with 4-phenyl-piperidine hydrochloride to give the title compound, Mp=168-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06153612 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-2fcc0812610e4b99852f0c02ab817859 |
| Source note | uspto-grants-2000_11 |