4-Phenylpiperidinium chloride → HCID 21697181, compound

HRID 1858968Notes

Reaction equation

HRID 1858968 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([CH2:16][C:17]([OH:19])=[O:18])[CH2:12][CH:13]([CH3:15])[CH3:14])(=[O:10])=[O:9])=[CH:4][CH:3]=1.Cl.[C:21]1([CH:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:12]([N:11]([CH2:16][C:17]([OH:19])=[O:18])[S:8]([C:5]1[CH:6]=[CH:7][C:2]([N:30]2[CH2:31][CH2:32][CH:27]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH2:28][CH2:29]2)=[CH:3][CH:4]=1)(=[O:10])=[O:9])[CH:13]([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 825094-Phenylpiperidinium chlorideHCID 21697167HCID 21697167, compound

Product 1

HCID 21697181HCID 21697181, compound

Procedure

In a manner similar to Example 3(b), [(4-fluoro-benzenesulfonyl)-isobutyl-amino]-acetic acid was condensed with 4-phenyl-piperidine hydrochloride to give the title compound, mp=140-143° C.

Sources & evidence

ORD record
ord-6bf4bfafc1bc46f68871331cc9d076cd
Source dataset
uspto-grants-2000_11
Patent number
US06153612

Reaction notes

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