HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidinium chloride → (S)-3-(4-Benzyloxy-phenyl)-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidinium chloride | HCID 82509 | — |
| Reactant | (S)-3-(4-benzyloxy-phenyl)-2-(4-fluoro-benzenesulfonylamino)-propionic acid | HCID 54304605 | — |
| Product | (S)-3-(4-Benzyloxy-phenyl)-2-[4-(4-phenyl-piperidin-1-yl)-benzenesulfonylamino]-propionic acid | HCID 12114675 | — |
Reaction Steps
In a manner similar to Example 3(b), (S)-3-(4-benzyloxy-phenyl)-2-(4-fluoro-benzenesulfonylamino)-propionic acid was condensed with 4-phenyl-piperidine hydrochloride to give the title compound, mp=75-78° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06153612 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-0ad8ca18b77e4fc6bbd543fbd1613abb |
| Source note | uspto-grants-2000_11 |