HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 2,2-Dimethyl-3-methylene-6-cyano-4-chromanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Chromanone | HCID 68110 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,2-Dimethyl-3-methylene-6-cyano-4-chromanone | HCID 14517982 | — |
Reaction Steps
A solution of 24 g of the chromanone, 12 g of paraformaldehyde and 24 ml of piperidine in 300 ml of ethanol is heated at 70° for 3 hours and evaporated. The residue is taken up in dichloromethane/petroleum ether 1:1, the mixture is filtered through silica gel and evaporated, and 2,2-dimethyl-3-methylene-6-cyano-4-chromanone is obtained as an unstable oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06153627 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-4772a91b0cfe4253a1d101172ae04117 |
| Source note | uspto-grants-2000_11 |