反应详情

To a solution of 1,3-indandione (43.8 g) and piperidine (44 mg) in dry benzene (500 ml) was added benzaldhyde (31.8 g). The mixture was heated to reflux and the water generated was removed by Dean-Stark trap. After 24 hours, the mixture was evaporated to dryness. The residue was recrystallized from ethanol (200 ml) to give 2-benzylidene-1,3-indandione as a yellow solid (50.6 g).

1. temperatureThe mixture was heated
2. temperatureto reflux
3. customthe water generated was removed by Dean-Stark trap
4. customthe mixture was evaporated to dryness
5. customThe residue was recrystallized from ethanol (200 ml)