Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859128Generated: November 2, 2026

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1859128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 2-fluoro-HCID 67979—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

Reaction Steps

Following General Procedure I' above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J' above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06153652
Source datasetuspto-grants-2000_11
ORD IDord-bfa9d9af14c746dc8aebd44342347ec2
Source noteuspto-grants-2000_11