Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859129Generated: October 31, 2026

2-(4-Fluorophenyl)acetic acid → 2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1859129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)acetic acidHCID 9837—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl esterHCID 54144399—

Reaction Steps

Following General Procedure I' above and using 4-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J' above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06153652
Source datasetuspto-grants-2000_11
ORD IDord-8d0e7c2b4eba4364a9d709ed1849557e
Source noteuspto-grants-2000_11