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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859132Generated: November 2, 2026

2-Thiopheneacetic acid → 2-[(2-Thienyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1859132

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetic acidHCID 15970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Thienyl)acetamido]butyric acid isobutyl esterHCID 54443682—

Reaction Steps

Following General Procedure I' above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J' above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06153652
Source datasetuspto-grants-2000_11
ORD IDord-28f9a0dda78941248ae871adafe446e5
Source noteuspto-grants-2000_11