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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859146Generated: November 2, 2026

p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

https://huagongshe.com/reaction/1859146

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(4-methylphenyl)acetyl]alanine iso-butyl esterHCID 53936136—

Reaction Steps

Following General Procedure I' above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure J' above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06153652
Source datasetuspto-grants-2000_11
ORD IDord-08a39596b973423bb03188a10d849bea
Source noteuspto-grants-2000_11