Trifluoroacetic acid → HCID 22122160, compound

Participants

Reaction Steps

A mixture of 3.65 g of 1-(2-azidoethyl)-4-(2,4-dimethoxybenzyl)-2,3-dioxopiperazine, 14.6 ml of trifluoroacetic acid and 7.3 ml of anisole was refluxed for 2 hours. The solvent was distilled off under reduced pressure and the resulting residue was purified by a silica gel column chromatography (eluent; chloroform:methanol=20:1) to obtain 1.8 g of 1-(2-azidoethyl)-2,3-dioxopiperazine as an oil.

Provenance & Evidence