Ethyl 4-bromobutyrate → HCID 22122177, compound

HRID 1859180Notes

Reaction equation

HRID 1859180 reaction equation
[CH3:1][O:2][C:3]1[CH:17]=[C:16]([O:18][CH3:19])[CH:15]=[CH:14][C:4]=1[CH2:5][N:6]1[CH2:11][CH2:10][NH:9][C:8](=[O:12])[C:7]1=[O:13].Br[CH2:21][CH2:22][CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25]>>[CH3:1][O:2][C:3]1[CH:17]=[C:16]([O:18][CH3:19])[CH:15]=[CH:14][C:4]=1[CH2:5][N:6]1[CH2:11][CH2:10][N:9]([CH2:21][CH2:22][CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:8](=[O:12])[C:7]1=[O:13]

Participants

3

Reactant 2

HCID 76300Ethyl 4-bromobutyrateHCID 127069801-[(2,4-Dimethoxyphenyl)methyl]piperazine-2,3-dione

Product 1

HCID 22122177HCID 22122177, compound

Procedure

1-(2,4-Dimethoxybenzyl)-2,3-dioxopiperazine was reacted with ethyl 4-bromobutyrate by the same method as in Reference Example 12 to obtain ethyl 4-[4-(2,4-dimethoxybenzyl)-2,3-dioxopiperazin-1-yl]butyrate as an oil.

Sources & evidence

ORD record
ord-47b9da9857874225b8f7c650ea35de1b
Source dataset
uspto-grants-2000_11
Patent number
US06153613

Reaction notes

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