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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18592Generated: October 27, 2026

Methyl 2,2,2-trichloroacetimidate → HCID 178499367, compound

https://huagongshe.com/reaction/18592

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2,2,2-trichloroacetimidateHCID 100479—
Reactant3,4-Diamino-5-(2,2,2-trifluoro-ethoxy)-thiophene-2-carboxylic acid methyl esterHCID 68617751—
ProductHCID 178499367HCID 178499367—

Reaction Steps

2-Trichloromethyl-6-(2,2,2-trifluoro-ethoxy)-3H-thieno[3,4-d]imidazole-4-carboxylic acid methyl ester was prepared by a procedure according to example 100 (i) from 500 mg (1.85 mmol) 3,4-diamino-5-(2,2,2-trifluoro-ethoxy)-thiophene-2-carboxylic acid methyl ester and 328.0 μl (2.59 mmol) 2,2,2-trichloro-acetimidic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741341B2
Source datasetuspto-grants-2010_06
ORD IDord-0e10d4148da54a2d8b795f2991ae3a69
Source noteuspto-grants-2010_06