反应详情

温度

125 °C

3-Methoxybenzenethiol(2.5 ml, 20.1 mmol) was added to 2-(4-methoxyphenyl)acrylic acid (3 g, 16.8 mmol) and stirred for 21 hours with heating at 125° C. The reaction solution was extracted with diethyl ether, and the ether solution was washed with 0.1N iodine-potassium iodide solution, water and saturated sodium chloride solution and dried over anhydrous magnesium sulfate. The residue was concentrated under reduced pressure to remove the organic solvent to obtain the title compound as a brown oil. The resulting compound was used in the next reaction without further purification.

1. extractionThe reaction solution was extracted with diethyl ether
2. washthe ether solution was washed with 0.1N iodine-potassium iodide solution, water and saturated sodium chloride solution
3. dry with materialdried over anhydrous magnesium sulfate
4. concentrationThe residue was concentrated under reduced pressure
5. customto remove the organic solvent