Acetic Acid → Acetic Anhydride

HRID 1859385Notes

Reaction equation

HRID 1859385 reaction equation
I([C:3]1[CH:8]=[CH:7][CH:6]=[C:5](CC([O-])=O)[C:4]=1[CH2:13][C:14]([O-:16])=[O:15])=O.[C:17]([OH:20])(=[O:19])[CH3:18]>>[C:3]1([O:20][CH2:17][CH2:18][CH2:7][CH2:8][CH2:3][CH2:4][CH2:5][CH3:6])[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1.[C:17]([O:16][C:14](=[O:15])[CH3:13])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 22180138HCID 22180138, compound

Product 2

HCID 7918Acetic AnhydrideHCID 74558Octyl phenyl ether

Procedure

To a mixture of 50 g of iodosobenzenediacetate obtained above, 30 g of octyl phenyl ether, 70 g of acetic anhydride and 725 ml of glacial acetic acid was dropwise added 8 g of concentrated sulfuric acid while cooling with an ice bath over a period of one hour. One hour after, a solution containing 31 g of sodium bromide dissolved in 150 ml of water was dropwise added thereto and the white powder thus-deposited was collected to obtain 42 g of iodonium bromide salt.

Sources & evidence

ORD record
ord-95d390f04f6749478da9736f02632c2a
Source dataset
uspto-grants-2003_03
Patent number
US06528229B2

Reaction notes

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