Ammonium cerium-nitrate → HCID 69945548, compound

Participants

Reaction Steps

The above crude compound 92 is dissolved in a THF/water mixture (311 ml, 17/1) and ammonium cerium nitrate (76 g, 138 mmol) is then added at 0° C. After stirring for 30 minutes, the reaction mixture is diluted with dichloromethane (1 l) and then washed with aqueous 2% sodium hydrogen carbonate solution, and then with water. After drying, filtration and concentration, the residue is purified on silica to give compound 93 (6.63 g, 72% over two steps).

Provenance & Evidence