Nitric Acid → 1-Bromo-4-tert-butyl-2-nitrobenzene

HRID 1859530Notes

Reaction equation

HRID 1859530 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:11])([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[N+:12]([O-])([OH:14])=[O:13].S(=O)(=O)(O)O>C(O)(=O)C>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:11])([CH3:10])[CH3:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 775951-Bromo-4-tert-butylbenzene

Product 1

HCID 112539061-Bromo-4-tert-butyl-2-nitrobenzene

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The reaction was done as described in General Method 12 using 1-bromo-4-tert-butyl-benzene (15 g), acetic acid (10 mL), nitric acid (6.5 g), and sulfuric acid (13 g), MS(APCI): 291.

Sources & evidence

ORD record
ord-e1e4795dc60c48889cd082cc7d150451
Source dataset
uspto-grants-2003_03
Patent number
US06528510B1

Reaction notes

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