HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Amino-4-methoxy-N-(4-methoxyphenyl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-nitrobenzoic acid | HCID 66640 | — |
| Product | 3-Amino-4-methoxy-N-(4-methoxyphenyl)-benzamide | HCID 16790431 | 64.4% |
Reaction Steps
Prepared according to the procedure described for Example 1 using oxalyl chloride (3.0 mL, 34.39 mmol), 4-methoxy-3-nitrobenzoic acid (5.00 g, 25.36 mmol), dimethylformamide (0.5 mL, 6.5 mmol), and 4-methoxyaniline (6.25 g, 50.7 mmol) to afford the product (4.45 g); m.p. 164-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528528B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-80aae0c8a3674e54bae84a4235978a62 |
| Source note | uspto-grants-2003_03 |