Methanol → Methyl 3-Amino-4-methoxybenzoate

HRID 1859679Notes

Reaction equation

HRID 1859679 reaction equation
OS(O)(=O)=O.[NH2:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=1[O:16][CH3:17])[C:10]([OH:12])=[O:11].[CH3:18]O>>[CH3:18][O:11][C:10](=[O:12])[C:9]1[CH:13]=[CH:14][C:15]([O:16][CH3:17])=[C:7]([NH2:6])[CH:8]=1

Participants

4

Reactant 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 178233-Amino-4-methoxybenzoic acid

Product 1

HCID 2734814Methyl 3-Amino-4-methoxybenzoate

Procedure

Concentrated H2SO4 (9 mL) was added in portions to a stirred solution of -3-amino-4-methoxybenzoic acid (20.06 g, 110.4 mmol) in methanol (280 mL).

Sources & evidence

ORD record
ord-5e560a8c8ee04a6483bede294d58e000
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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