3-Amino-4-methoxybenzanilide → HCID 54394707, compound

HRID 1859684Notes

Reaction equation

HRID 1859684 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:6].[Cl:19][C:20]1[CH:21]=[C:22]([N:26]=[C:27]=[S:28])[CH:23]=[CH:24][CH:25]=1>>[Cl:19][C:20]1[CH:21]=[C:22]([NH:26][C:27](=[S:28])[NH:1][C:2]2[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:5]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:6])[CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 754493-Chlorophenyl isothiocyanate

Product 1

HCID 54394707HCID 54394707, compoundYield 77.1%

Procedure

Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.218 g, 0.90 mmol) and 3-chlorophenyl isothiocyanate (0.12 mL, 0.92 mmol) to give the product (0.286 g); m.p. 165-168° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e64c31fc91d94e2597bba3fa3cc87694
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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