HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-methoxybenzanilide → 3-[3-(3-Cyanophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| Reactant | 3-Cyanophenyl isothiocyanate | HCID 76578 | — |
| Solvent | Dichloromethane ethylacetate | HCID 21226138 | — |
| Product | 3-[3-(3-Cyanophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide | HCID 54153620 | 84.4% |
Reaction Steps
Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.972 g, 4.0 mmol) and 3-cyanophenyl isothiocyanate (0.649 g, 4.0 mmol). Trituration in boiling ethyl acetate/dichloromethane (1:1) gave the product (1.358 g); m.p. 183-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528528B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-c9b8a552da0148b6937160c1e9b3f4b9 |
| Source note | uspto-grants-2003_03 |