反应详情

1.80 g (7.43 mmol) 1-(2-Methoxy-ethoxy)-2,3-dinitro-benzene were dissolved in 250 mL MeOH. The solution was evacuated and rinsed with argon several times. 250 mg palladium on charcoal (10%) were added and again the mixture was evacuated and rinsed with argon several times. Finally argon was exchanged by hydrogen (balloon filled with hydrogen) and the mixture was stirred for 2 h at room temperature. The reaction mixture was filtered over “Celite” and the filter residue was washed with 100 mL MeOH. The filtrate was concentrated under vacuo to give pure 3-(2-Methoxy-ethoxy)-benzene-1,2-diamine as a brown oil. Yield: 1.33 g MS (ES+): m/e=183.

1. customThe solution was evacuated
2. washrinsed with argon several times
3. addition250 mg palladium on charcoal (10%) were added
4. customagain the mixture was evacuated
5. washrinsed with argon several times
6. filtrationThe reaction mixture was filtered over “Celite”
7. washthe filter residue was washed with 100 mL MeOH
8. concentrationThe filtrate was concentrated under vacuo