HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-methoxybenzanilide → 4-Methoxy-N-phenyl-3-(3-pyridin-3-yl-thioureido)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| Reactant | 3-Pyridyl isothiocyanate | HCID 2737242 | — |
| Product | 4-Methoxy-N-phenyl-3-(3-pyridin-3-yl-thioureido)-benzamide | HCID 86583810 | 95.2% |
Reaction Steps
Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.972 g, 4.00 mmol) and 3-pyridyl isothiocyanate (0.565 g, 4.15 mmol). Trituration in hexanes/ethyl acetate (3:2) gave the product (1.441 g); m.p. 178-179° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528528B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-4e7a14ede876467fa7013f06eda87c03 |
| Source note | uspto-grants-2003_03 |