3-Amino-4-methoxybenzanilide → HCID 17921773, compound

HRID 1859705Notes

Reaction equation

HRID 1859705 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:6].[N+:19]([C:22]1[CH:27]=[CH:26][C:25]([N:28]=[C:29]=[S:30])=[CH:24][CH:23]=1)([O-:21])=[O:20]>CCOCC>[CH3:18][O:17][C:16]1[CH:15]=[CH:14][C:4]([C:5]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:6])=[CH:3][C:2]=1[NH:1][C:29]([NH:28][C:25]1[CH:24]=[CH:23][C:22]([N+:19]([O-:21])=[O:20])=[CH:27][CH:26]=1)=[S:30]

Participants

4

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 75044Benzene, 1-isothiocyanato-4-nitro-

Product 1

HCID 17921773HCID 17921773, compoundYield 81.8%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.976 g, 4.02 mmol) and 4-nitrophenyl isothiocyanate (0.723 g, 4.02 mmol) to afford the product (1.39 g) after trituration in ether; m.p. 183-184° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b18f7c3700344d198ae6ed38316606a8
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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