HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Tolylisothiocyanate → N-(3,4-Dimethylphenyl)-4-methoxy-3-(3-m-tolyl-thioureido)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Tolylisothiocyanate | HCID 69304 | — |
| Reactant | 3-Amino-4-methoxy-N-(3,4-dimethylphenyl)-benzamide | HCID 16786027 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-(3,4-Dimethylphenyl)-4-methoxy-3-(3-m-tolyl-thioureido)-benzamide | HCID 54106240 | 52.4% |
Reaction Steps
A solution of 3-amino-N-(3,4-dimethylphenyl)-4-methoxy-benzamide from Example 6 (0.541 g, 2.00 mmol) and 3-methylphenyl isothiocyanate (0.28 mL, 2.07 mmol) in ethyl acetate (35 mL) was boiled until nearly all the solvent had evaporated. Filtration after 2 days at room temperature afforded the product (0.44 g) in two crops; m.p. 155-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528528B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-fe5c534287ad45aa9807dc5193f89104 |
| Source note | uspto-grants-2003_03 |