m-Tolylisothiocyanate → HCID 54422588, 화합물

HRID 1859718노트

반응식

HRID 1859718 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[C:5]([NH:7][C:8]1[CH:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH3:15])[CH:9]=1)=[O:6].[CH3:21][C:22]1[CH:23]=[C:24]([N:28]=[C:29]=[S:30])[CH:25]=[CH:26][CH:27]=1>>[CH3:15][C:10]1[CH:9]=[C:8]([NH:7][C:5](=[O:6])[C:4]2[CH:16]=[CH:17][C:18]([O:19][CH3:20])=[C:2]([NH:1][C:29]([NH:28][C:24]3[CH:23]=[C:22]([CH3:21])[CH:27]=[CH:26][CH:25]=3)=[S:30])[CH:3]=2)[CH:13]=[C:12]([CH3:14])[CH:11]=1

참가 물질

3

반응물 2

HCID 69304m-TolylisothiocyanateHCID 167939593-Amino-4-methoxy-N-(3,5-dimethylphenyl)-benzamide

생성물 1

HCID 54422588HCID 54422588, 화합물수율 48.6%

실험 절차

Prepared according to the procedure described for Example 102 using 3-amino-N-(3,5-dimethylphenyl)4-methoxy-benzamide from Example 11 (0.542 g, 2.01 mmol) and 3-methylphenyl isothiocyanate (0.28 mL, 2.07 mmol) to afford the product (0.41 g); m.p. 188-189° C.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-8896d50671fe4f6a8e7810aecf46e722
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06528528B2

반응 노트

불러오는 중…