3-Amino-4-methoxybenzanilide → HCID 18626256, compound

HRID 1859729Notes

Reaction equation

HRID 1859729 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([S:10](Cl)(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[NH2:14][C:15]1[CH:16]=[C:17]([CH:27]=[CH:28][C:29]=1[O:30][CH3:31])[C:18]([NH:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]>>[N+:1]([C:4]1[CH:5]=[C:6]([S:10]([NH:14][C:15]2[CH:16]=[C:17]([CH:27]=[CH:28][C:29]=2[O:30][CH3:31])[C:18]([NH:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:19])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 84763-Nitrobenzenesulfonyl chloride

Product 1

HCID 18626256HCID 18626256, compoundYield 82.4%

Procedure

Prepared according to the procedure described for Example 121 using 3-nitrobenzenesulfonyl chloride (2.44 g, 10 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10.0 mmol) to afford the product (3.522 g); m.p. 208-210° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-cbf73ebe43214ec18d8cf7b920aaf32f
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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