3-Amino-4-methoxybenzanilide → 3-(Butane-1-sulfonylamino)-4-methoxy-N-phenyl-benzamide

HRID 1859733Notes

Reaction equation

HRID 1859733 reaction equation
[CH2:1]([S:5](Cl)(=[O:7])=[O:6])[CH2:2][CH2:3][CH3:4].[NH2:9][C:10]1[CH:11]=[C:12]([CH:22]=[CH:23][C:24]=1[O:25][CH3:26])[C:13]([NH:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:14]>>[CH2:1]([S:5]([NH:9][C:10]1[CH:11]=[C:12]([CH:22]=[CH:23][C:24]=1[O:25][CH3:26])[C:13]([NH:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:14])(=[O:7])=[O:6])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 754301-Butanesulfonyl chloride

Product 1

HCID 186261903-(Butane-1-sulfonylamino)-4-methoxy-N-phenyl-benzamideYield 92%

Procedure

Prepared according to the procedure described for Example 128 using 1-butanesulfonyl chloride (0.47 g, 3.0 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (0.73 g, 3.0 mmol) to afford the product (1.0 g); m.p. 182-183° C. after recrystallization from ethanol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a4d61bd7a43042e088f3ec582c1ae284
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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