3-Amino-4-methoxybenzanilide → HCID 18626058, compound

HRID 1859735Notes

Reaction equation

HRID 1859735 reaction equation
[C:1]([NH:4][C:5]1[S:6][C:7]([S:11](Cl)(=[O:13])=[O:12])=[C:8]([CH3:10])[N:9]=1)(=[O:3])[CH3:2].[NH2:15][C:16]1[CH:17]=[C:18]([CH:28]=[CH:29][C:30]=1[O:31][CH3:32])[C:19]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:20]>>[C:1]([NH:4][C:5]1[S:6][C:7]([S:11]([NH:15][C:16]2[CH:17]=[C:18]([CH:28]=[CH:29][C:30]=2[O:31][CH3:32])[C:19]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:20])(=[O:13])=[O:12])=[C:8]([CH3:10])[N:9]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 969512-Acetamido-4-methylthiazole-5-sulfonyl chloride

Product 1

HCID 18626058HCID 18626058, compoundYield 50.7%

Procedure

Prepared according to the procedure described for Example 126 using 2-acetamido-4-methyl-5-thiazolesulfonyl chloride (0.76 g, 3.0 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (0.73 g, 3.0 mmol) to afford the product (0.7 g); m.p. 260-261° C. after trituration in diethyl ether.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9f56d319b1434f53bde7679b49b14ca0
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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