Sodium Hydroxide → 2-Butyl-3-[4-[2-(4'-carboxybiphenyl-4-carbonylamino)ethoxy]phenyl]propionic acid

Participants

Reaction Steps

In a similar manner to that described in Example 2, ethyl 2-butyl-3-[4-[2-(4′-methoxycarbonylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate (243 mg), which is the product of Reference example 12, was reacted with aqueous sodium hydroxide solution (1N, 1.83 ml) and the reaction mixture was treated to give the title compound (163 mg) as a white powder.

Provenance & Evidence