HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-[4-[2-(4'-Chlorobiphenyl-4-carbonylamino)ethoxy]phenyl]-2-phenoxypropionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 3-[4-[2-(4'-chlorobiphenyl-4-carbonylamino)ethoxy]phenyl]-2-phenoxypropionate | HCID 18626003 | — |
| Product | 3-[4-[2-(4'-Chlorobiphenyl-4-carbonylamino)ethoxy]phenyl]-2-phenoxypropionic acid | HCID 10255962 | 74.7% |
Reaction Steps
In a similar manner to that described in Example 2, ethyl 3-[4-[2-(4′-chlorobiphenyl-4-carbonylamino)ethoxy]phenyl]-2-phenoxypropionate (900 mg), which is the product of Example 79, was reacted with aqueous sodium hydroxide solution (1N, 5.00 ml) and the reaction mixture was treated to give the title compound (638 mg) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-9b100e05334242c1b4674948685711dd |
| Source note | uspto-grants-2003_03 |