Sodium Hydroxide → 2-Phenylamino-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionic acid

HRID 1859931Notes

Reaction equation

HRID 1859931 reaction equation
[C:1]1([NH:7][CH:8]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][CH2:23][NH:24][C:25](=[O:38])[C:26]3[CH:31]=[CH:30][C:29]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][N:33]=4)=[CH:28][CH:27]=3)=[CH:17][CH:16]=2)[C:9]([O:11]CC)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+]>CO>[C:1]1([NH:7][CH:8]([CH2:14][C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][CH2:23][NH:24][C:25](=[O:38])[C:26]3[CH:27]=[CH:28][C:29]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][N:33]=4)=[CH:30][CH:31]=3)=[CH:17][CH:16]=2)[C:9]([OH:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 18625947Ethyl 2-phenylamino-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionate

Product 1

HCID 177956082-Phenylamino-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 2-phenylamino-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionate is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Sources & evidence

ORD record
ord-55a7133459b14072be0df1934ee3eecb
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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