Sodium Hydroxide → HCID 18625716, compound

HRID 1859932Notes

Reaction equation

HRID 1859932 reaction equation
Cl.[C:2]1([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:7]=[CH:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][O:13][C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH:21]([NH:27][CH2:28][CH3:29])[C:22]([O:24]CC)=[O:23])=[CH:16][CH:15]=2)=[O:9])=[CH:4][CH:3]=1.[OH-].[Na+]>CO>[C:2]1([C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH:3]=[CH:4][C:5]([C:8]([NH:10][CH2:11][CH2:12][O:13][C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH:21]([NH:27][CH2:28][CH3:29])[C:22]([OH:24])=[O:23])=[CH:16][CH:15]=2)=[O:9])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 18625966HCID 18625966, compound

Product 1

HCID 18625716HCID 18625716, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 3-[4-[2-(biphenyl-4-carbonylamino)ethoxy]phenyl]-2-ethylaminopropionate hydrochloride, which is the product of Example 177(b), is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Sources & evidence

ORD record
ord-15a6f89a77ec434d868811f582ad8f0a
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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