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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859933Generated: October 30, 2026

Sodium Hydroxide → 2-(N-ethyl-N-phenylamino)-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionic acid

https://huagongshe.com/reaction/1859933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 2-(N-ethyl-N-phenylamino)-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionateHCID 18625991—
SolventMethanolHCID 887—
Product2-(N-ethyl-N-phenylamino)-3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]propionic acidHCID 17795769—

Reaction Steps

Ethyl 2-(N-ethyl-N-phenylamino)-3-[4-[2-(4-pyridine-2-ylbenzoylamino)-ethoxy]phenyl]propionate, which is the product in Example 179, is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-65077979a85a4986b0c44784e516bfd2
Source noteuspto-grants-2003_03