Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859939Generated: October 29, 2026

Sodium Hydroxide → 3-[4-[2-(Biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionic acid

https://huagongshe.com/reaction/1859939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 3-[4-[2-(4-phenylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionateHCID 18625789—
SolventMethanolHCID 887—
Product3-[4-[2-(Biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionic acidHCID 18625959—

Reaction Steps

Ethyl 3-[4-[2-(4-phenylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionate, which is the product of Example 193, is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-5ffba238a711439bb32b36dda0dab40a
Source noteuspto-grants-2003_03