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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859948Generated: October 30, 2026

Sodium hydride → HCID 18625778, compound

https://huagongshe.com/reaction/1859948

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantBenzene, (2-bromoethoxy)-HCID 68526—
ReactantHCID 18625736HCID 18625736—
ProductHCID 18625778HCID 1862577878.5%

Reaction Steps

In a similar manner to that described in Reference example 2(a), a reaction was carried out using diethyl 2-(4-methoxymethoxybenzyl)malonate (1.58 g), which is the product of Reference example 3(b), sodium hydride (55% suspension in oil, 0.24 g) and 2-phenoxyethyl bromide (1.23 g) and the reaction mixture was treated to afford the desired compound (1.72 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-9eae7447b0c043ecb70aec259d008e83
Source noteuspto-grants-2003_03