Potassium Hydroxide → HCID 18625752, compound

HRID 1859949Notes

Reaction equation

COC[O:4][C:5]1[CH:31]=[CH:30][C:8]([CH2:9][C:10]([CH2:21][CH2:22][O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)(C(OCC)=O)[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:7][CH:6]=1.[OH-].[K+]>>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([CH2:9][CH:10]([CH2:21][CH2:22][O:23][C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:30][CH:31]=1

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 18625778HCID 18625778, compound

Product 1

HCID 18625752HCID 18625752, compoundYield 100.1%

Procedure

In a similar manner to that described in Reference example 2(b), a reaction was carried out using diethyl 2-(4-methoxymethoxybenzyl)-2-(2-phenoxyethyl)malonate (1.71 g) and potassium hydroxide and the reaction mixture was treated to afford the desired compound (1.25 g) as a syrup.

Workup

additionthe reaction mixture was treated

Sources & evidence

ORD record: ord-bc9b913b6de444568649d46ad36deb42
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06528525B1

Reaction notes

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