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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859966Generated: November 1, 2026

Potassium Carbonate → HCID 18625713, compound

https://huagongshe.com/reaction/1859966

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-(2-Bromoethoxy)tetrahydro-2H-pyranHCID 86621—
ReactantHCID 18625931HCID 18625931—
SolventDimethylformamideHCID 6228—
ProductHCID 18625713HCID 18625713100.1%

Reaction Steps

In a similar manner to that described in Reference example 3(e), a reaction was carried out using ethyl 3-(4-hydroxyphenyl)-2-(4-isopropylphenoxy)propionate (14.8 g), which is the product of Reference example 5(d), 2-(2-bromoethoxy)tetrahydropyran (28.2 g) and potassium carbonate (24.9 g) in dimethylformamide and the reaction mixture was treated to afford the desired compound (20.6 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-97410f526ec542ae989f35aef6124f27
Source noteuspto-grants-2003_03