HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18625915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Diethyl butylmalonate | HCID 67244 | — |
| Reactant | 4-Benzyloxybenzyl chloride | HCID 70042 | — |
| Product | HCID 18625915 | HCID 18625915 | 89.1% |
Reaction Steps
In a similar manner to that described in Reference example 2(a), a reaction was carried out using diethyl 2-butylmalonate (2.16 g), 4-benzyloxybenzyl chloride (2.44 g) and sodium hydride (55% suspension in oil, 480 mg) and the reaction mixture was treated to afford the desired compound (3.67 g) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-cd2c8f332ab2412b875cb97437c1edb9 |
| Source note | uspto-grants-2003_03 |