p-Toluenesulfonic acid monohydrate → Ethyl 2-butyl-3-[4-(2-hydroxyethoxy)phenyl]propionate

Participants

Reaction Steps

In a similar manner to that described in Reference example 3(f), a reaction was carried out using ethyl 2-butyl-3-[4-[2-(tetrahydropyran-2-yloxy)ethoxy]phenyl]propionate (2.47 g), which is the product of Reference example 6(d), and p-toluenesulfonic acid monohydrate (1.24 g) and the reaction mixture was treated to afford the desired compound (1.44 g) as a syrup.

Provenance & Evidence