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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859975Generated: October 31, 2026

Sodium Azide → Ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butylpropionate

https://huagongshe.com/reaction/1859975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AzideHCID 33557—
ReactantEthyl 2-butyl-3-[4-(2-methanesulfonyloxyethoxy)phenyl]propionateHCID 18625769—
ProductEthyl 3-[4-(2-azidoethoxy)phenyl]-2-butylpropionateHCID 18625797114.5%

Reaction Steps

In a similar manner to that described in Reference example 3(h), a reaction was carried out using ethyl 2-butyl-3-[4-(2-methanesulfonyloxyethoxy)phenyl]propionate (1.65 g), which is the product of Reference example 6(f), and sodium azide (0.95 g) and the reaction mixture was treated to afford the desired compound (1.62 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-4a235c9f9ce14c91a9b8bb5369b909ad
Source noteuspto-grants-2003_03