HCID 18625922, compound → HCID 18625714, compound

HRID 1859980Notes

Reaction equation

HRID 1859980 reaction equation
C([O:8][C:9]1[CH:31]=[CH:30][C:12]([CH2:13][C:14]([CH3:29])([CH2:20][CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:10]=1)C1C=CC=CC=1>[Pd]>[OH:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:13][C:14]([CH3:29])([CH2:20][CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:30][CH:31]=1

Participants

3

Reactant 1

HCID 18625922HCID 18625922, compound

Product 1

HCID 18625714HCID 18625714, compoundYield 107.2%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 2-(4-benzyloxybenzyl)-2-methyl-5-phenylvalerate (1.88 g), which is the product of Reference example 7(c), and palladium on carbon (5%, 0.28 g) and the reaction mixture was treated to afford the desired compound (1.58 g) as a syrup.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-c2e7b22228e540daa7f4f911e3bf1915
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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