HCID 18625985, compound → HCID 18625981, compound

HRID 1859985Notes

Reaction equation

HRID 1859985 reaction equation
[N:1]([CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]([CH3:29])([CH2:20][CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:9][CH:8]=1)=[N+]=[N-]>[Pd]>[NH2:1][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][C:14]([CH3:29])([CH2:20][CH2:21][CH2:22][C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:12]=1

Participants

3

Reactant 1

HCID 18625985HCID 18625985, compound

Product 1

HCID 18625981HCID 18625981, compoundYield 99.6%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-[4-(2-azidoethoxy)phenyl]-2-methyl-2-(3-phenylpropyl)propionate (0.86 g), which is the product of Reference example 7(h), and palladium on carbon (5%, 129 mg) and the reaction mixture was treated to afford the title compound (0.80 g) as a syrup.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-09ba5878ba3447029a7b4c13ef83c266
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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