HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 18625739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2-Bromoethoxy)tetrahydro-2H-pyran | HCID 86621 | — |
| Reactant | Ethyl 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionate | HCID 11220314 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 18625739 | HCID 18625739 | 72.4% |
Reaction Steps
In a similar manner to that described in Reference example 3(e), a reaction was carried out using ethyl 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionate (1.55 g), which is the product of Reference example 8(b), 2-(2-bromoethoxy)tetrahydropyran (1.08 g) and potassium carbonate (2.14 g) in dimethylacetamide and the reaction mixture was treated to afford the desired compound (1.60 g) as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-3c6f5fa8ddf64459899b9e9d9c24a5a7 |
| Source note | uspto-grants-2003_03 |