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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859988Generated: November 1, 2026

Potassium Carbonate → HCID 18625739, compound

https://huagongshe.com/reaction/1859988

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-(2-Bromoethoxy)tetrahydro-2H-pyranHCID 86621—
ReactantEthyl 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionateHCID 11220314—
SolventDimethylacetamideHCID 31374—
ProductHCID 18625739HCID 1862573972.4%

Reaction Steps

In a similar manner to that described in Reference example 3(e), a reaction was carried out using ethyl 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionate (1.55 g), which is the product of Reference example 8(b), 2-(2-bromoethoxy)tetrahydropyran (1.08 g) and potassium carbonate (2.14 g) in dimethylacetamide and the reaction mixture was treated to afford the desired compound (1.60 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-3c6f5fa8ddf64459899b9e9d9c24a5a7
Source noteuspto-grants-2003_03