HCID 18625830, compound → HCID 18626008, compound

HRID 1859994Notes

Reaction equation

HRID 1859994 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16]([O:23][C:24]2[CH:29]=[CH:28][C:27]([CH:30]([CH3:32])[CH3:31])=[CH:26][CH:25]=2)([CH3:22])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1)C1C=CC=CC=1>[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16]([O:23][C:24]2[CH:25]=[CH:26][C:27]([CH:30]([CH3:31])[CH3:32])=[CH:28][CH:29]=2)([CH3:22])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1

Participants

3

Reactant 1

HCID 18625830HCID 18625830, compound

Product 1

HCID 18626008HCID 18626008, compoundYield 85.7%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-(4-isopropylphenoxy)-2-methylpropionate (6.16 g), which is the product of Reference example 9(a), and palladium on carbon (5%, 1.00 g) and the reaction mixture was treated to afford the title compound (4.18 g) as a syrup.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-bcb52b68341b4cacaf4a1c9e0cb0d734
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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