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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860006Generated: November 1, 2026

Ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionate → Ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butyl-2-methylpropionate

https://huagongshe.com/reaction/1860006

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionateHCID 18625962—
CatalystPalladiumHCID 23938—
ProductEthyl 3-[4-(2-aminoethoxy)phenyl]-2-butyl-2-methylpropionateHCID 1862580996.1%

Reaction Steps

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionate (2.73 g), which is the product of Reference example 10(f), and palladium on carbon (5%, 270 mg) and the reaction mixture was treated to afford the title compound (2.42 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-e9a9009166a24c7fbf2181f16b036ea2
Source noteuspto-grants-2003_03