HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionate → Ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butyl-2-methylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionate | HCID 18625962 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butyl-2-methylpropionate | HCID 18625809 | 96.1% |
Reaction Steps
In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butyl-2-methylpropionate (2.73 g), which is the product of Reference example 10(f), and palladium on carbon (5%, 270 mg) and the reaction mixture was treated to afford the title compound (2.42 g) as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-e9a9009166a24c7fbf2181f16b036ea2 |
| Source note | uspto-grants-2003_03 |