Methyl 4-(3-formylphenyl)benzoate → HCID 18626005, compound

HRID 1860012Notes

Reaction equation

[CH:1]([C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([O:17][CH3:18])=[O:16])=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1)=[O:2].[CH:19]([O-])([O-])[O:20]C.F[C:25](F)(C(F)F)COC1C=CC(C(NCCOC2C=CC(CC(OC3C=CC(C(C)C)=CC=3)C(O)=O)=CC=2)=O)=CN=1>>[CH3:25][O:2][CH:1]([O:20][CH3:19])[C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([O:17][CH3:18])=[O:16])=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1

Participants

Reactant 3

HCID 4321386Methyl 4-(3-formylphenyl)benzoate

HCID 18625926HCID 18625926, compound

HCID 53629101Methylorthoformate

Product 1

HCID 18626005HCID 18626005, compound

Procedure

In a similar manner to that described in Example 11(a), a reaction was carried out using methyl 3′-formylbiphenyl-4-carboxylate (1.60 g), which is the product of Reference example 14(a), methyl orthoformate (3.64 ml) and amberlyst 15 (160 mg) and the reaction mixture was treated to afford the desired compound (1.91 g) as a syrup.

Workup

additionthe reaction mixture was treated

Sources & evidence

ORD record: ord-5bee55ef510b4ae58da12f6df59bf424
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06528525B1

Reaction notes

Loading…