1,1'-Carbonyldiimidazole → Ethyl 2-butyl-3-[4-[2-(3'-dimethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate

Participants

Reaction Steps

In a similar manner to that described in Example 5, a reaction was carried out using ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butylpropionate (1.55 g), which is the product of Reference example 6, 3′-dimethoxymethylbiphenyl-4-carboxylic acid (1.44 g), which is the product of reference example 14(c), and carbonyldiimidazole (1.03 g) and the reaction mixture was treated to afford the desired compound (2.72 g) as a syrup.

Provenance & Evidence