1,1'-Carbonyldiimidazole → Ethyl 2-butyl-3-[4-[2-(3'-methoxymethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate

Participants

Reaction Steps

In a similar manner to that described in Example 5, a reaction was carried out using ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butylpropionate (358 mg), which is the product of Reference example 6, 3′-methoxymethoxymethylbiphenyl-4-carboxylic acid (333 mg), which is the product of reference example 15(c), and carbonyldiimidazole (238 mg) and the reaction mixture was treated to afford the desired compound (573 mg) as a brown syrup.

Provenance & Evidence