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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860019Generated: October 31, 2026

Sodium Hydroxide → Sodium 2-butyl-3-[4-[2-(3'-methoxymethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate

https://huagongshe.com/reaction/1860019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 2-butyl-3-[4-[2-(3'-methoxymethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionateHCID 18625844—
ProductSodium 2-butyl-3-[4-[2-(3'-methoxymethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionateHCID 23694239—

Reaction Steps

In a similar manner to that described in Example 2, a reaction was carried out using ethyl 2-butyl-3-[4-[2-(3′-methoxymethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate (573 mg), which is the product of Reference example 15(d), and aqueous sodium hydroxide (1N, 2.00 ml) and the reaction mixture was treated to afford the desired compound (472 mg) as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-b4985030eafa4f80a40cd6f4779a3c79
Source noteuspto-grants-2003_03