HCID 14742620, compound → HCID 18625901, compound

HRID 1860033Notes

Reaction equation

HRID 1860033 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH:16]([CH2:22][CH2:23][CH3:24])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1)C1C=CC=CC=1>[Pd]>[OH:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH:16]([CH2:22][CH2:23][CH3:24])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:13][CH:14]=1

Participants

3

Reactant 1

HCID 14742620HCID 14742620, compound

Product 1

HCID 18625901HCID 18625901, compoundYield 107.1%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-propylpropionate (4.00 g) and palladium on carbon (5%, 0.40 g) and the reaction mixture was treated to afford the desired compound (3.10 g) as a syrup.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-2a484942e2e340858e5041b2d1909a40
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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